abstract：:Summary Long-chain acyl-CoA synthetase (ACSL) catalyses the formation of long-chain acyl-CoA from fatty acid, ATP and CoA, activating fatty acids for subsequent reactions. Long-chain acyl-CoA synthetase thus plays an essential role in both lipid biosynthesis and fatty acid degradation. The ACSL4 gene was evaluated as ...

journal_title：Animal genetics

authors： Mercadé A,Estellé J,Pérez-Enciso M,Varona L,Silió L,Noguera JL,Sánchez A,Folch JM

更新日期：2006-06-01 00:00:00

abstract：:The aim of the study was to investigate quantitative trait loci (QTL) in previously identified regions of chicken chromosomes 1, 4 and 5 relating to 40-day body weights and conformation scores. Half-sib (HS) and variance component analyses were implemented and compared using QTL Express software. Data were from a two-...

journal_title：Animal genetics

authors： Rowe SJ,Windsor D,Haley CS,Burt DW,Hocking PM,Griffin H,Vincent J,De Koning DJ

更新日期：2006-06-01 00:00:00

abstract：:We report the identification of quantitative trait loci (QTL) affecting carcass composition, carcass length, fat deposition and lean meat content using a genome scan across 462 animals from a combined intercross and backcross between Hampshire and Landrace pigs. Data were analysed using multiple linear regression fitt...

journal_title：Animal genetics

authors： Karlskov-Mortensen P,Bruun CS,Braunschweig MH,Sawera M,Markljung E,Enfält AC,Hedebro-Velander I,Josell A,Lindahl G,Lundström K,von Seth G,Jørgensen CB,Andersson L,Fredholm M

更新日期：2006-04-01 00:00:00

abstract：:To clarify the structure of the porcine genomic region that contains quantitative trait loci (QTL) related to fat, we constructed a bacterial artificial chromosome (BAC) contig of the region from DST to SRPK1 on porcine chromosome 7 and performed low-redundancy 'skim' shotgun sequencing of the clones that composed a m...

journal_title：Animal genetics

authors： Tanaka M,Suzuki K,Morozumi T,Kobayashi E,Matsumoto T,Domukai M,Eguchi-Ogawa T,Shinkai H,Awata T,Uenishi H

更新日期：2006-02-01 00:00:00

abstract：:Ovine hereditary chondrodysplasia, or spider lamb syndrome (SLS), is a genetic disorder that is characterized by severe skeletal abnormalities and has resulted in substantial economic losses for sheep producers. Here we demonstrate that a non-synonymous T>A transversion in the highly conserved tyrosine kinase II domai...

journal_title：Animal genetics

authors： Beever JE,Smit MA,Meyers SN,Hadfield TS,Bottema C,Albretsen J,Cockett NE

更新日期：2006-02-01 00:00:00

abstract：:We have previously identified and mapped porcine expressed sequence tags (ESTs) derived from genes that are preferentially expressed in liver. The aim of the present study was to identify single nucleotide polymorphisms (SNPs) in porcine genes encoding enzymes in hepatic metabolic pathways and use the SNPs for mapping...

journal_title：Animal genetics

authors： Ponsuksili S,Chomdej S,Murani E,Bläser U,Schreinemachers HJ,Schellander K,Wimmers K

更新日期：2005-12-01 00:00:00

abstract：:Numerous mapping studies of complex traits in the pig have resulted in quantitative trait loci (QTL) intervals of 10-20 cM. To improve the chances to identify the genes located in such intervals, increased expressed sequence tags (EST)-based marker density, coupled with comparative mapping with species whose genomes h...

journal_title：Animal genetics

authors： Demeure O,Pomp D,Milan D,Rothschild MF,Tuggle CK

更新日期：2005-10-01 00:00:00

abstract：:The objective of this study was to identify twinning rate quantitative trait loci (QTL) by typing pooled samples in a preliminary screening followed by interval mapping to test QTL effects. Four elite North American Holstein half-sib sire families with high twinning rate predicted transmitting abilities (PTA) were use...

journal_title：Animal genetics

authors： Cobanoglu O,Berger PJ,Kirkpatrick BW

更新日期：2005-08-01 00:00:00

abstract：:The bacterial artificial clone-based physical map for chicken plays an important role in the integration of the consensus linkage map and the whole-genome shotgun sequence. It also provides a valuable resource for clone selection within applications such as fluorescent in situ hybridization and positional cloning. How...

journal_title：Animal genetics

authors： Aerts JA,Veenendaal T,van der Poel JJ,Crooijmans RP,Groenen MA

更新日期：2005-06-01 00:00:00

abstract：:The Siamese cat has a highly recognized coat colour phenotype that expresses pigment at the extremities of the body, such as the ears, tail and paws. This temperature-sensitive colouration causes a 'mask' on the face and the phenotype is commonly referred to as 'pointed'. Burmese is an allelic variant that is less tem...

journal_title：Animal genetics

authors： Lyons LA,Imes DL,Rah HC,Grahn RA

更新日期：2005-04-01 00:00:00

abstract：:Atlantic salmon have been reared in the British Columbia, Canada aquaculture industry since the early 1980s. No breeding programmes spanned the entire production period and pedigree records were not kept for broodstocks prior to or since importation. Of the three recognized industry strains, two are of European ancest...

journal_title：Animal genetics

authors： Withler RE,Supernault KJ,Miller KM

更新日期：2005-02-01 00:00:00

abstract：:A high-resolution comprehensive map was constructed for porcine chromosome (SSC) 6, where quantitative trait loci (QTL) for reproduction and meat quality traits have been reported to exist. A radiation hybrid (RH) map containing 105 gene-based markers and 15 microsatellite markers was constructed for this chromosome u...

journal_title：Animal genetics

authors： Cao H,Robinson JA,Jiang Z,Melville JS,Golovan SP,Jones MW,Verrinder Gibbins AM

更新日期：2004-10-01 00:00:00

abstract：:The quantitative assessment of genetic diversity within and between populations is important for decision-making in genetic conservation plans. In our study, we applied the livestock core set method to define the contribution of 15 cattle breeds, 11 of which are Portuguese indigenous cattle breeds, to genetic diversit...

journal_title：Animal genetics

authors： Mateus JC,Eding H,Penedo MC,Rangel-Figueiredo MT

更新日期：2004-08-01 00:00:00

abstract：:A linkage map of the Japanese quail (Coturnix japonica) genome was constructed based upon segregation analysis of 72 microsatellite loci in 433 F(2) progeny of 10 half-sib families obtained from a cross between two quail lines of different genetic origins. One line was selected for long duration of tonic immobility, a...

journal_title：Animal genetics

authors： Kayang BB,Vignal A,Inoue-Murayama M,Miwa M,Monvoisin JL,Ito S,Minvielle F

更新日期：2004-06-01 00:00:00

abstract：:Tibial dyschondroplasia (TD) is a genetic leg defect in broilers with a lesion of avascular, non-calcified cartilage below the growth plate of the proximal tibiatarsus. This disease is considered to result from the inability of chondrocytes to undergo terminal differentiation. Thyroid hormones are required for chondro...

journal_title：Animal genetics

authors： Shen S,Berry W,Jaques S,Pillai S,Zhu J

更新日期：2004-04-01 00:00:00

abstract：:Classification and regression tree (CART) modelling was used to determine infectious hypodermal and haematopoietic necrosis virus (IHHNV) resistance and susceptibility in Penaeus stylirostris. In a previous study, eight random amplified polymorphic DNA (RAPD) markers and viral load values using real-time quantitative ...

journal_title：Animal genetics

authors： Hizer SE,Wright TM,Garcia DK

更新日期：2004-02-01 00:00:00

abstract：:Nineteen cattle bones from the Viking 10th and early 11th century levels in Dublin were assessed for presence of reliable genotypes from three autosomal markers. Due to the good preservational condition of the samples, it was possible to amplify and type at least two out of three of the microsatellite markers (CSRM60,...

journal_title：Animal genetics

authors： Edwards CJ,Connellan J,Wallace PF,Park SD,McCormick FM,Olsaker I,Eythórsdóttir E,MacHugh DE,Bailey JF,Bradley DG

更新日期：2003-12-01 00:00:00

abstract：:The chromosomal localization of 13 bovine genes was determined using radiation hybrid (RH) mapping. The RH mapping data were in agreement with published data using either linkage, somatic cell hybrids or in situ hybridization. Mutation analysis using single-stranded conformational polymorphism, restriction fragment le...

journal_title：Animal genetics

authors： Haegeman A,Williams JL,Law A,Van Zeveren A,Peelman LJ

更新日期：2003-10-01 00:00:00

abstract：:We present herein a bovine chromosome 24 (BTA24) radiation hybrid (RH) map using 40 markers scored on a panel of 90 RHs. Of these markers, 29 loci were ordered with odds of at least 1000:1 in a framework map. An average retention frequency of 17.4% was observed, with relatively higher frequencies near the centromere. ...

journal_title：Animal genetics

authors： Kurar E,Womack JE,Kirkpatrick BW

更新日期：2003-06-01 00:00:00

abstract：:A fragment of mitochondrial DNA (mtDNA) control region (approximately 700 bp) was sequenced in 104 individuals from 20 breeds (three Chinese domestic breeds, five recently derived breeds and 12 introduced breeds) of domestic rabbits, Oryctolagus cuniculus. Nineteen sites were polymorphic, with 18 transitions and one i...

journal_title：Animal genetics

authors： Long JR,Qiu XP,Zeng FT,Tang LM,Zhang YP

更新日期：2003-04-01 00:00:00

abstract：:Seventy-five individuals of Bubalus bubalis belonging to four different breeds, three of river buffalo and one of swamp buffalo, were studied for polymorphism in MHC DRB (Bubu-DRB) and DRA (Bubu-DRA) loci. Eight alleles of Bubu-DRB were found, and all alleles in the swamp type were shared with the three river breeds. ...

journal_title：Animal genetics

authors： Sena L,Schneider MP,Brenig B,Honeycutt RL,Womack JE,Skow LC

更新日期：2003-02-01 00:00:00

abstract：:Cytochrome P450-aromatase enzyme (CYP19), which catalyses the conversion of androgens to oestrogens, is critical in ovarian differentiation and hence in the sex differentiation pathways of non-mammalian vertebrates. As in other fish species, distinct ovarian and brain aromatase genes have been identified in the Nile T...

journal_title：Animal genetics

authors： Harvey SC,Kwon JY,Penman DJ

更新日期：2003-02-01 00:00:00

abstract：:The polymorphism at the PvuII recognition site in the ESR gene showed no statistically significant association with sow productivity traits in a Meishan x Large White F2 population. Estimates of the effect on litter size were, however, in the opposite direction and statistically different from previously published est...

journal_title：Animal genetics

authors： Gibson JP,Jiang ZH,Robinson JA,Archibald AL,Haley CS

更新日期：2002-12-01 00:00:00

abstract：:The progressive loss of colour in the hair of grey horses is controlled by a dominantly inherited allele at the Grey locus (GG). In this study, two paternal Quarter Horse (QH) families segregating for the GG allele were genotyped with a set of 101 microsatellite markers spanning the 31 autosomes and the X chromosome. ...

journal_title：Animal genetics

authors： Locke MM,Penedo MC,Bricker SJ,Millon LV,Murray JD

更新日期：2002-10-01 00:00:00

abstract：:An MspI polymorphism was identified in intron 13 of the equine homologue of proto-oncogene c-kit (KIT) by comparing DNA sequences from horses with solid coat colour and horses homozygous for the tobiano spotting (To) gene. The allele associated with solid coat colour was designated KM0, while the allele associated wit...

journal_title：Animal genetics

authors： Brooks SA,Terry RB,Bailey E

更新日期：2002-08-01 00:00:00

abstract：:The objectives of this study were to assign both microsatellite and gene-based markers on porcine chromosome X to two radiation hybrid (RH) panels and to develop a more extensive integrated map of SSC-X. Thirty-five microsatellite and 20 gene-based markers were assigned to T43RH, and 16 previously unreported microsate...

journal_title：Animal genetics

authors： McCoard SA,Fahrenkrug SC,Alexander LJ,Freking BA,Rohrer GA,Wise TH,Ford JJ

更新日期：2002-06-01 00:00:00

abstract：:The melanocortin-4 receptor (MC4R), a G-protein coupled receptor, is implicated in mediating the effect of leptin on food intake and energy balance. A previous candidate gene study reported an association between an MC4R missense mutation (Asp298Asn) and fatness, growth and feed intake in pigs. To assess this associat...

journal_title：Animal genetics

authors： Park HB,Carlborg O,Marklund S,Andersson L

更新日期：2002-04-01 00:00:00

abstract：:Previous research has mapped an ovulation rate quantitative trait locus (QTL) to bovine chromosome 19. In an effort to enhance comparative mapping information and develop additional markers for refined QTL mapping, microsatellite markers were developed in a targeted approach. A bovine bacterial artificial chromosome (...

journal_title：Animal genetics

authors： Kirkpatrick BW,Byla B,Kurar E,Warren WC

更新日期：2002-02-01 00:00:00

abstract：:The Japanese quail (Coturnix japonica; JQ) is one of the domesticated fowl species of Japan. To provide DNA sequence information for examination of its phylogenetic position in the order Galliformes, the complete sequence of the JQ mitochondria was determined. Sequence analysis revealed that the JQ mitochondrial genom...

journal_title：Animal genetics

authors： Nishibori M,Hayashi T,Tsudzuki M,Yamamoto Y,Yasue H

更新日期：2001-12-01 00:00:00

abstract：:The inheritance pattern of the skeletal muscle hypertrophy phenotype caused by the callipyge gene has been characterized as polar overdominance. We hypothesized that this trait may be caused by a gain or loss of gene expression because of the reversible nature of the phenotype in paternal vs. maternal inheritance. Sup...

journal_title：Animal genetics

authors： Bidwell CA,Shay TL,Georges M,Beever JE,Berghmans S,Cockett NE

更新日期：2001-10-01 00:00:00

abstract：:Comparative anchor tagged sequence (CATS) consensus primers from loci mapped to human chromosomes 9, 10, 20, and 22 have been used to amplify homologous loci in pigs. Of 53, CATS primers tested in pigs, only 23 yielded products homologous to the human locus (42% success). Ten loci were physically mapped (43% success r...

journal_title：Animal genetics

authors： Lee JH,Zhang W,Moran C

更新日期：2001-10-01 00:00:00

abstract：:The London strain of rainbow trout (Oncorhynchus mykiss) was created by interbreeding three other strains of rainbow trout and therefore was expected to have higher levels of genetic variation than other strains of rainbow trout. We examined 129 London strain rainbow trout from Indiana by allozyme electrophoresis to a...

journal_title：Animal genetics

authors： Gregg RE,Rhodes OE,Armstrong G

更新日期：2001-08-01 00:00:00

abstract：:Six distinct serotypes of the chicken B blood group system (which encodes the major histocompatibility complex) were identified in a commercial broiler breeder line (Line C). The B serotypes were compared by B-G restriction fragment length polymorphism (RFLP) analysis, allele-specific PCR typing test for B-LBII family...

journal_title：Animal genetics

authors： Livant EJ,Zheng D,Johnson LW,Shi W,Ewald SJ

更新日期：2001-06-01 00:00:00

abstract：:The goal of this study was to identify and map genes expressed during the elongation phase of embryogenesis in swine. Expressed sequence tags were analysed from a previously described porcine cDNA library prepared from elongating swine embryos. Average insert length of randomly selected clones was approximately 600 bp...

journal_title：Animal genetics

authors： Smith TP,Fahrenkrug SC,Rohrer GA,Simmen FA,Rexroad CE,Keele JW

更新日期：2001-04-01 00:00:00

abstract：:The goat CSN1S2 locus is characterized by the presence of three alleles, A, B and C, all associated with about 2.5 g/l of protein per allele. The SDS-PAGE analysis of 441 individual milk samples obtained from goats belonging to a population reared in Southern Italy showed that the milk produced by three goats did not ...

journal_title：Animal genetics

authors： Ramunno L,Longobardi E,Pappalardo M,Rando A,Di Gregorio P,Cosenza G,Mariani P,Pastore N,Masina P

更新日期：2001-02-01 00:00:00

abstract：:A bovine genomic large-insert bacterial artificial chromosome (BAC) library has been constructed from leukocytes of a Holstein-Friesian male. Size fractionated DpnII-digested genomic DNA was ligated to the dephosphorylated BamH1 ends of a pBACe3.6 vector. Approximately 8.3 x 10(4) individual BAC clones were picked int...

journal_title：Animal genetics

authors： Buitkamp J,Kollers S,Durstewitz G,Welzel K,Schäfer K,Kellermann A,Lehrach H,Fries R

更新日期：2000-12-01 00:00:00

abstract：:Work on Belgian Blue cattle revealed that an 11 base pair (bp) deletion within the bovine myostatin gene (GDF8) is associated with the double-muscled phenotype seen in this breed. Investigations focusing on other European breeds known to show double-muscling identified several mutations within the coding region of the...

journal_title：Animal genetics

authors： Smith JA,Lewis AM,Wiener P,Williams JL

更新日期：2000-10-01 00:00:00

abstract：:We have examined whether black/yellow coat colour in Labrador retrievers is controlled by allelic variants at the extension locus. As the gene encoding the melanocyte-stimulating hormone receptor (MC1R) has been shown to correspond to the extension locus in several species, we have determined the genomic MC1R sequence...

journal_title：Animal genetics

authors： Everts RE,Rothuizen J,van Oost BA

更新日期：2000-06-01 00:00:00

abstract：:The use of the AFLP (amplified fragment length polymorphism) technique for the characterization of highly inbred Iberian pig breed genotypes and the detection of strain-specific polymorphisms is demonstrated. Twelve different primer combinations were used on individual DNA samples from animals belonging to two black h...

journal_title：Animal genetics

authors： Ovilo C,Cervera MT,Castellanos C,Martínez-Zapater JM

更新日期：2000-04-01 00:00:00

abstract：:Partition of the genetic variability, genetic structure and relationships among seven Spanish Celtic horse breeds were studied using PCR amplification of 13 microsatellites on 481 random individuals. In addition, 60 thoroughbred horses were included. The average observed heterozygosity and the mean number of alleles w...

journal_title：Animal genetics

authors： Cañon J,Checa ML,Carleos C,Vega-Pla JL,Vallejo M,Dunner S

更新日期：2000-02-01 00:00:00